How does Cushing's disease affect dogs?

Understanding Cushing's Disease in Dogs

Cushing's disease, also known as hyperadrenocorticism, is a hormonal disorder that occurs when a dog's body produces excessive amounts of cortisol, a hormone that helps regulate various functions in the body, including stress response, metabolism, and immune function. This condition can significantly impact a dog's health and quality of life.

### Symptoms:
The symptoms of Cushing's disease in dogs can vary but typically include:
1. **Increased thirst and urination**: Dogs may drink more water and urinate more frequently.
2. **Increased appetite**: Affected dogs often show an increase in hunger, which can lead to weight gain.
3. **Abdominal distension**: The belly may appear swollen or enlarged due to fat accumulation.
4. **Thin skin and hair loss**: Dogs may experience thinning of the skin, hair loss, and easy bruising.
5. **Lethargy**: Affected dogs may seem more tired than usual and less active.
6. **Recurrent infections**: Due to a suppressed immune system, dogs may be more prone to infections.

### Diagnosis:
To diagnose Cushing's disease, veterinarians typically perform a combination of physical examinations, blood tests, urinalysis, and imaging studies such as ultrasound. The most common tests include the ACTH stimulation test and the low-dose dexamethasone suppression test.

### Treatment:
Treatment options for Cushing's disease depend on the underlying cause (pituitary or adrenal gland tumor) and may include:
1. **Medications**: Drugs like trilostane (Vetoryl) or mitotane can help manage cortisol production.
2. **Surgery**: In cases of adrenal tumors, surgical removal may be an option.
3. **Regular monitoring**: Ongoing veterinary check-ups are essential to adjust treatment and monitor the dog's response to therapy.

### Management:
Dogs with Cushing's disease require lifelong management. It's crucial for pet owners to work closely with their veterinarian to develop a treatment plan tailored to their dog's specific needs. Regular exercise, a balanced diet, and maintaining a healthy weight can also help improve the dog's overall well-being.

In conclusion, while Cushing's disease can be a serious condition, with proper diagnosis and treatment, many dogs can lead comfortable and fulfilling lives.

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